Diagnosis of arterial thrombosis and stenosis in blood vessel Using bioimpedance analysis

Bio-impedance Analysis had been used in the medical field and research with over 70 years. This technique enable a non-invasive and low-cost diagnosis of a wide range of cardiovascular pathology. It permits the access to impedance changes caused by pathophysiological processes in living tissue and allows to the diagnosis several vascular anomalies such as arterial and venous diseases (stenosis, aneuvrism and thrombosis). The objective of this paper is to evaluate the influence of an arterial constriction as a stenosis and thrombosis on the Bioimpedance signal. In order to evaluate the effects of stenosis diseases on the electrical impedance a computational fluid dynamics software (COMSOL Multiphysics) was applied. The fluid structure interaction (FSI) and Electric Currents (EC) module are used to study the effect of the changes on Young modulus which simulates atherosclerotic lesions in first step and change of stenosis severity in the second step. The study shows that increase on young modulus induce a diminution of the magnitude of the impedance signal and a supplementary oscillation in the impedance curve. The increase in stenosis severity causes a diminution of the magnitude of impedance signal but no change on the signal morphology has been detected.